Why do people get Alzheimer’s?

Several factors are believed to play an important role in the development of the disease

Alzheimer’s disease is one of the most common forms of dementia, affecting millions of people worldwide. But why do people get Alzheimer’s? While researchers have not yet identified a definitive cause, several factors are believed to play a significant role in the development of the disease. Here, we explore some of the main contributing factors.

Genetic factors

Genetics play a significant role in the risk of developing Alzheimer’s. Certain genes, such as APOE-e4, have been linked to an increased risk of the disease. If a close relative has Alzheimer’s, the risk of developing the disease yourself is higher. There are also rare genetic mutations that directly cause an inherited form of Alzheimer’s, but these cases are very uncommon.

Age

Age is the most significant risk factor for Alzheimer’s disease. Most people affected are over 65 years old. The risk of developing Alzheimer’s roughly doubles every five years after the age of 65. Although Alzheimer’s can sometimes occur earlier, it is much less common.

Lifestyle and health

Lifestyle factors and overall health also have a significant impact on the risk of developing Alzheimer’s. Cardiovascular diseases, high blood pressure, diabetes, smoking, and obesity are all linked to an increased risk. Research also shows that physical activity, a balanced diet, and mental stimulation can help reduce the risk of Alzheimer’s.

Environmental factors

Environmental factors, such as exposure to air pollution or toxic substances, may also influence the risk of Alzheimer’s. Although these connections are still being studied, some research suggests that long-term exposure to harmful substances can negatively affect brain health.

 

 

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